Jin Hyuk is a genius neurosurgeon with a cold and severe attitude in his interactions with other people due to his personal pursuit of perfection. Through a mysterious power, Jin Hyuk finds himself transported back in time 150 years. He begins treating people there, but the lack of necessary implements and rudimentary medical knowledge of the period forces him to seek new ways to aid the sick. Through this challenging process, Jin Hyuk eventually becomes a genuine doctor.

An ordinary college student, Lee Seol, finds out she's a princess. The grandson of Daehan Group, Park Hae Young, is put in charge of educating Seol on proper etiquette.

The drama will be about two men whose fates are crossed from the very first day that they were born. Both men were born in the same hospital. When he was a teenager, Lee Dong Chul witnessed the death of his father. From then on he promised to seek revenge on the man who caused his father's death, Shin Tae Hwan. But unbeknownst to everybody is the fact that Dong Chul's younger brother, Dong Wook, was switched at birth with Tae Hwan's son, Myung Hun. Dong Wook grows up to become a prosecutor and vows to help his brother seek revenge. But what happens when they find out that they're not brothers? What will Dong Chul do when he finds out that his real brother was raised by Shin Tae Hwan and that the brother that was beside him all these years is the son of his enemy?

Yoo Min-woo's (Song Seung Heon) first love was Soh Eun-hye (Shin Ae). No love was greater than the love between these two...until Eun-hye get's into a car accident. Eun-hye dies...leaving one thing left behind...her heart. Shim Hye-won (Son Yeh Jin) has suffered from a terrible heart disease ever since childhood. Miraculously she finds that she will be obtaining a heart from a donor, Soh Eun-hye.

Suffering from the pain of a heartache, Min-woo goes to Paris to study...the memories of Eun-hye still rest in his heart. When he returns to Korea, fate takes a turn and brings Hye-won and Min-woo together. When the two first meet, Hye-won's heart (Eun-hye's heart), oddly beats faster when she is around Min-woo.

Park Jung-jae (Ryu Jin) is Hye-won's boyfriend. Park Jung-ah (Han Ji Hye) is Jung-jae's sister and she meets Min-woo in Italy and falls for him...

Hye-won doesn't know why or what she feels when she's with Min-woo...and Min-woo feels guilt toward Eun-hye, because the feeling of love rises once again as he continues to see Hye-won...

A story on how a righteous lawyer trying to set up his law firm with friends. Some may be harbouring different motives or reasons to help him out initially. They are influenced by him to take up worthwhile cases in the end.

Yoon Joon-suh (Song Seung Heon) and Yoon Eun-suh (Song Hye Gyo) always thought they were siblings. Eun-suh is in fact from a different family because she was switched at birth, but no one knows about this fact until one day, when Eun-suh is in a car accident. Her blood is tested only to discover that her blood type is completely different from her brother's proving that they are not related at all.