Family is like a haven to us. We love them even to pick the stars and the moon for them. In this drama, a family, whose members are all scattered away due to the conflicts, comes to realize that it’s each other that will best protect them from hardships.Seo Jin Woo is a surgeon who has a trauma from his younger days that causes surgery phobia, Han Chae Won works in food research and deeply in love of Jin Woo, and the ambitious Kyung Joo who abandoned Jin Woo to choose Min Hyuk. Together, they depicts the story of love and hate.

A drama that deals with the brain and neurosurgeons.

Lee Kang Hoon (Shin Ha Kyun), who graduated from the top medical school, works at the top hospital, and is the top neurosurgeon around. Basically, he’s Brain No. 1. (And he works on brains, too!) He has ambitions to become the director at his university hospital. He is obsessed with success, which is probably both his greatest flaw and strength, since it makes him steely and fierce.

However, once he meets his sunbae Kim Sang Chul (Jung Jin Young), the prickly genius doctor and world famous neurologist, he turns over a new leaf and becomes a sincere doctor. Seo Joon Suk (Jo Dong Hyuk) is a doctor and will become Lee Kang Hoon’s rival. Yoon Ji Hye (Choi Jung Won) is also a neurosurgeon who grew up in an ordinary family. She is extremely strict in matters of work and study, but has a warm bedside manner with her patients.

Set in a tumultuous period where the political scene is murky and various people fought to gain power and the throne, the young king will do anything to strengthen his shaky position in court. His childhood friend Baek Rok leads a secret military force loyal to the king, called the "Black Cloud Swords." Baek Rok lives for his king, his brother Baek Kyul and his lover Jung Yeon, but when his ambitious brother betrays him and leads him into a trap, he finds himself on the run. He becomes a slave and gladiator, eventually returning to Joseon to seek revenge.

This drama is a story about love, family, and the realism of people’s dreams! Each character will experience their joy, frustration, and pain at times as they live out their daily lives. Na Dan Poong is a company marketing team leader. Jang Hyun Woo is a plastic surgeon and Baek Ho's friend. Sun Jae is good looking, smart, and makes very good decisions. He has a girlfriend, Ji Young, who he met while they were in college. But to farther his ambitions, he breaks up with Ji Young to marry Bong Soo Ah whose father is the owner of Bonjour Foods.

Jo Dong Hyuk will be playing a 27 year old single with a six year old son who falls for Choo Sang Mi, a thirty-three year old divorcee. Her husband cheated on her and she suffers from the pain of losing their son in a car accident 3 years ago. This drama is about how the two meet and through a child they heal each other wounds.

Yoon Seok Joo is a producer who abandons his common law wife, Seo Young, to attain success. They have a daughter together but he later betrays Seo Young when he marries a rich man's daughter, Lee Jung Min. Lee Sang Min is an owner of a film company and is a new film director. He is also Jung Min's half brother. Sang Min will be a rival to Seok Joo in work and in love for Seo Young. Yoon Hyun Joo lost her dad at a young age and went through serious hardships and became a successful architect and is Seok Joo's sister. This drama is also about the lives of five siblings.

Yoon Hyun Suh (played by Ahn Jae Wook) is an adoptee who grows up in the United States. He becomes successful as a top manager of a hotel chain. He is assigned to do business in Korea. He falls in love with Choi Young In (played by Lee Bo Young), a sassy concierge from the hotel he is assigned to. There is trouble still looming because Kang Soo Jin (played by Oh Yoon Ah) who is Hyun Suh's best friend's ex-wife comes back with vengeance in mind. The three become entagled in this love triangle.