Seo Eun Young and Kang Jung Woo are happy, engaged-to-be-married couple. Suddenly, when Eun Young was pregnant, Jung Woo abandoned her to marry Na Kyung, a rich woman. The new couple then went to study abroad for 5 years. Meanwhile, Eun Young works as a nurse in a hospital. Kang Hyung Woo, who is one of her patients, becomes obsessed with her. Hyung Woo’s mother, Madam Shin, a department store owner, then wants Eun Young to marry her son.
Rookie detective Jeong-Min (Kim Dong-Wuk) finds difficulties with his new job. His boss doesn’t like him, he has to secretly prepare for a public service exam, and the local residents are up in arms over a serial killer that the police can’t catch. A protest is then organized in front of the police station by the local residents. To Jeong-Min’s horror, his own mother leads the protest as she works as the general affairs manager for the women’s association. The residents are particularly peeved that the serial killer is causing the value of their homes to drop. Jeong-Min then decides that he will catch the serial killer once and for all.
Choi Gi Chan is an University Botanic Professor with the "perfect genes." The drama is about an editor of a fashion magazine, Kim Dang Ja, who suddenly develops an urge to have her own baby despite opposing the idea of marriage. The story will talk about Dang Ja striving to look for a man with perfect genes to accomplish her mission. Gi Chan happens to be her "target" in order for her to accomplish her mission. The story later develops as Dang Ja must persuade him to do it without any commitments, which is a problem because Gi Chan doesn't believe in the idea of sex before marriage.